VIROLOGY:MOLECULAR BIOLOGY AND PATHOGENESIS

This book from others is the author’s fascination with the diversity of the viruses and their adaptation to the condition of the host organism. And he takes the reader on his journey through the exciting world of viruses.” –Pharmazie in unserer Zeit, 4/2010 (review in German) Based on the author’s experiences teaching virology for more than 35 years, this book enables readers to develop a deep understanding of fundamental virology by emphasizing principles and discussing viruses in the context of virus families. Moreover, individual virus families are examined within the context of the Baltimore classification system, a key unifying theme that allows readers to assume basic facts about the replication strategy of a virus based on the nature of its genome. The first chapter provides an historical overview, followed by a chapter introducing the principles of animal virus classification and the Baltimore classification system. The next chapter explores the various modes of virus infection and disease. Chapter 4 then considers host defenses against microorganisms and viral countermeasures to subvert those host defenses. Armed with a solid foundation in basic principles, readers move on to eighteen subsequent chapters, each one dedicated to a particular virus family. These chapters detail the organization of the viral genome and its pattern of expression, with additional discussions covering viral structure, entry, assembly, release, and associated medical issues.

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